Race for iron: impact of siderophore- and heme-mediated networking on spatial interactions in defined microbial communities (B01)
Competition for the key nutrient iron significantly shapes microbial networking. The secretion of Fe3+-complexing siderophores, the uptake of heme as alternative iron source and the production of iron storage proteins represent important homeostatic strategies in bacteria. In this project, we will analyse competitive and cooperative strategies for the acquisition of iron and heme in synthetic microbial communities involving prokaryotic and eukaryotic microbial model organisms. Tailored microfluidic cultivation devices mimicking structured environments and the application of optogenetic switches and in vivo biosensors will enable us to determine the spatial and temporal dynamics of interspecies networking in the microbial race for iron.
Team
© Sascha Kreklau
apl. Prof. Dr. Thomas Drepper
Principal Investigator
+49 2461 61-4173
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Institute of Molecular Enzyme Technology (IMET)
Bacterial Photobiotechnology
Heinrich Heine University Düsseldorf
Forschungszentrum Jülich GmbH
Wilhelm-Johnen-Straße
Gebäude: 15.8 / 2. OG
Etage/Raum: 402
Prof. Dr. Julia Frunzke
Principal Investigator
+49 2461/61-5430
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Institute of Bio- and Geosciences
Department: Bacterial Networks and Interactions
Forschungszentrum Jülich
Wilhelm-Johnen-Straße
Gebäude: 15.4
Etage/Raum: 239
Dr. Dietrich Kohlheyer
Principal Investigator
+49 2461 61-2875
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Institute of Microscale Bioengineering
(IBG-1)
Forschungszentrum Jülich GmbH
Wilhelm-Johnen-Straße
Gebäude: 15.7
Etage/Raum: 201